Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ACCS Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 9.0E-07 0.522 0.731 161 3
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 194 9
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692 70 3
OAS3 Q9Y6K5 2'-5'-oligoadenylate synthetase 3 Enzyme 2.0E-33 0.608 0.615 72 15
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 399 8
OGFOD1 Q8N543 2-oxoglutarate and iron dependent oxygenase domain containing 1 3.3E-17 0.839 0.231 5 0
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 216 12
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 154 15
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 52 9
HACD1 B0YJ81 3-hydroxyacyl-CoA dehydratase 1 1.3E-09 0.539 0.846 160 0
BDH1 Q02338 3-hydroxybutyrate dehydrogenase 1 Enzyme 7.6E-08 0.729 0.423 23 1
BDH2 Q9BUT1 3-hydroxybutyrate dehydrogenase 2 8.5E-08 0.700 0.462 26 0
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 77 0
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 102 9
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 376 7
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 149 24
NT5C3A Q9H0P0 5'-nucleotidase, cytosolic IIIA Enzyme 1.5E-02 0.593 0.692 80 15
ATIC P31939 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Enzyme 3.0E-19 0.576 0.731 100 4
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 140 9
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 289 34
HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C Ion channel 2.6E-10 0.769 0.192 16 3
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 245 30
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 207 22
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 104 1