Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 191
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 135
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 153
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 48
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 70
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 137
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 80
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 94
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 85
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 168
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 91
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 218
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 148
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 307