Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 22
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885 20
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
BCL2L1 Q07817 BCL2 like 1 Signaling 0.94 0.493 0.885 17
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 15
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 15
CFL1 P23528 cofilin 1 0.56 0.529 0.769 14
ALAD P13716 aminolevulinate dehydratase Enzyme 5.6E-05 0.556 0.615 13
HCN1 O60741 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.00 0.564 0.654 13
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846 12
HRH3 Q9Y5N1 histamine receptor H3 G-protein coupled receptor 4.1E-02 0.647 0.462 12
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 11
GHSR Q92847 growth hormone secretagogue receptor G-protein coupled receptor 6.6E-03 0.528 0.769 11
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846 11
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731 10
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808 10
IL6ST P40189 interleukin 6 signal transducer Signaling 1.00 0.475 0.808 10
MFN1 Q8IWA4 mitofusin 1 Enzyme 2.5E-10 0.644 0.577 10
PTK2B Q14289 protein tyrosine kinase 2 beta Kinase 0.94 0.448 0.808 10
SLC8A1 P32418 solute carrier family 8 member A1 Transporter 1.00 0.544 0.769 10
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885 9