Source: MGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 4
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 4
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 3
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 3
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923 3
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 3
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 3
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 2
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 2
DMD P11532 dystrophin 1.00 0.423 0.923 2
FLNB O75369 filamin B 6.1E-10 0.458 0.923 2
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 2
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 2
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923 2
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923 2
FZD4 Q9ULV1 frizzled class receptor 4 G-protein coupled receptor 0.97 0.490 0.923 2
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 1
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923 1
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 1
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 1
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 1
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 1
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 1