Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 72
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 67
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 59
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 55
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 53
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 53
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 53
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 51
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 46
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 37
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 36
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 35
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 33
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 33
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 30
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 27
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 27
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 25
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 21
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 20
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923 19
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 19
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923 12