Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 5
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 33
PPP6C O00743 protein phosphatase 6 catalytic subunit 0.86 0.729 0.231 2
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 27
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962 3
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 2
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 9
STAG2 Q8N3U4 stromal antigen 2 Nucleic acid binding 1.00 0.568 0.731 12
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808 17
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 39
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 2
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846 4
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808 4