Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 1044 15
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 1011 8
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 995 85
IL2 P60568 interleukin 2 0.48 0.336 0.885 950 5
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 933 59
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 875 79
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 859 12
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 854 163
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 821 17
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 819 26
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 770 23
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 747 2600
MIR21 microRNA 21 0.363 0.846 726 2
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 715 92
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 711 47
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 703 681
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0