Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CDH1 P12830 cadherin 1 0.15 0.401 0.808 73 158
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 71 57
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 68 14
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 67 40
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 67 16
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 67 4
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62 3
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 60 11
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 59 11
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 58 9
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 56 43
SLC12A5 Q9H2X9 solute carrier family 12 member 5 Transporter 1.00 0.570 0.654 55 19
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 53 5
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885 52 33
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 52 1
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 52 1
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 49 395
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 49 40
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 49 1
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 48 121
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 48 17
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808 47 223