Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 821 17
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 819 26
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 816 119
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 770 23
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 754 47
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 747 2600
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 739 23
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 737 18
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 731 141
MIR21 microRNA 21 0.363 0.846 726 2
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 724 10
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 711 47
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 703 681