Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
VIM P08670 vimentin 0.71 0.372 0.846 51 4
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 49 395
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 48 35
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 48 2
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808 48 1
TF P02787 transferrin Enzyme 4.1E-08 0.527 0.846 47 70
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 44 8
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731 44 3
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 42 277
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885 42 4
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 42 0
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 41 2
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846 39 5
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808 39 3
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 39 1
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 38 38
LTF P02788 lactotransferrin Enzyme 1.3E-21 0.543 0.846 37 8
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 36 107
TTR P02766 transthyretin Transporter 0.52 0.423 0.885 36 54
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885 36 0
KRT8 P05787 keratin 8 2.4E-08 0.517 0.654 35 7
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846 35 4
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 35 0
DHFR P00374 dihydrofolate reductase Enzyme 3.4E-02 0.513 0.808 34 3