Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1511 83
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1254 10
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1119 24
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 1101 12
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 1083 13
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 1018 185
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 724 10
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846 557 3
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885 520 4
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 483 11
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846 460 26
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846 460 15
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885 444 5
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 416 57
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846 369 7
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923 335 6
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 301 402
MYDGF Q969H8 myeloid derived growth factor 3.5E-06 0.451 0.846 295 3
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846 272 3