Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 32 28
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 26 8
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 22 11
TNXB P22105 tenascin XB 1.9E-02 0.572 0.731 19 35
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 19 5
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 13 10
PLCE1 Q9P212 phospholipase C epsilon 1 Enzyme 5.7E-11 0.572 0.654 10 18
CNNM2 Q9H8M5 cyclin and CBS domain divalent metal cation transport mediator 2 1.00 0.641 0.346 10 5
AMPD3 Q01432 adenosine monophosphate deaminase 3 Enzyme 1.1E-12 0.743 0.385 9 7
CACNB2 Q08289 calcium voltage-gated channel auxiliary subunit beta 2 Ion channel 2.7E-06 0.659 0.538 9 7
PHACTR1 Q9C0D0 phosphatase and actin regulator 1 Enzyme modulator 0.64 0.663 0.423 8 8
SLC39A8 Q9C0K1 solute carrier family 39 member 8 Transporter 0.67 0.584 0.769 8 1
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 7 9
ULK4 Q96C45 unc-51 like kinase 4 Kinase 4.4E-38 0.722 0.385 6 507
MMP26 Q9NRE1 matrix metallopeptidase 26 Enzyme 5.4E-11 0.650 0.615 6 35
WNT3 P56703 Wnt family member 3 Signaling 0.88 0.536 0.808 6 17
MSRA Q9UJ68 methionine sulfoxide reductase A Enzyme 1.5E-15 0.608 0.615 6 7
ATP2B1 P20020 ATPase plasma membrane Ca2+ transporting 1 Transporter 1.00 0.666 0.500 6 5
ZNF831 Q5JPB2 zinc finger protein 831 7.9E-10 0.792 0.192 6 4
CASC8 cancer susceptibility 8 0.670 0.462 5 15
BORCS7-ASMT BORCS7-ASMT readthrough (NMD candidate) 0.805 0.154 5 7
SOX6 P35712 SRY-box transcription factor 6 1.00 0.578 0.615 5 6
BANK1 Q8NDB2 B cell scaffold protein with ankyrin repeats 1 4.8E-12 0.653 0.538 5 5
PLEKHA7 Q6IQ23 pleckstrin homology domain containing A7 6.2E-09 0.729 0.423 5 4