Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1174 54
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1034 6
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 672 82
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846 559 1
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846 526 2
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 490 42
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885 476 673
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885 473 7
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846 456 10
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846 451 5
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 443 30
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 410 66
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 369 52
SMN2 Q16637 survival of motor neuron 2, centromeric 0.10 0.459 0.769 299 35
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885 276 99
TNFRSF11A Q9Y6Q6 TNF receptor superfamily member 11a 8.8E-03 0.480 0.846 270 22
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885 245 14
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846 243 42
TFPI P10646 tissue factor pathway inhibitor Enzyme modulator 0.25 0.486 0.808 230 6