| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 | 382 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 | 283 |
| HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 | 229 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 | 221 |
| BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 | 186 | |
| CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | 160 | |
| ARID2 | Q68CP9 | AT-rich interaction domain 2 | 1.00 | 0.543 | 0.808 | 105 | |
| NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | 85 | |
| SF3B1 | O75533 | splicing factor 3b subunit 1 | Nucleic acid binding | 1.00 | 0.511 | 0.731 | 56 |
| IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | 55 | |
| FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 | 22 |