Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 213
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885 212
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769 208
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 206
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 202
TRNL1 tRNA 0.534 0.731 194
VCP P55072 valosin containing protein 1.00 0.469 0.923 193
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769 190
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808 188
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769 186
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 179
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769 175
TRNW tRNA 0.563 0.731 175
TRNS1 tRNA 0.555 0.808 170
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692 168
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731 168
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 155
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808 153
COX3 P00414 cytochrome c oxidase III Enzyme 0.546 0.808 151
TRNS2 tRNA 0.579 0.731 145
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885 143
TREX1 Q9NSU2 three prime repair exonuclease 1 0.58 0.517 0.808 142
NSUN2 Q08J23 NOP2/Sun RNA methyltransferase 2 Enzyme 2.6E-04 0.559 0.846 140
TRNF tRNA 0.582 0.731 139