Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1899 59
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 1082 82
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 666 9
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 644 54
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 623 23
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808 575 144
SST P61278 somatostatin Signaling 0.34 0.399 0.885 535 4
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923 511 9
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 498 158
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 490 42
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 482 61
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 392 101
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885 392 9
ENG P17813 endoglin 1.00 0.446 0.846 371 114
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 369 52
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846 369 4
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885 295 142
SLC17A5 Q9NRA2 solute carrier family 17 member 5 Transporter 6.9E-10 0.491 0.808 252 47
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731 226 4