BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
125
|
84 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
107
|
343 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
86
|
26 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
85
|
55 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
84
|
390 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
71
|
21 |
H3-3A |
P84243
|
H3.3 histone A
|
|
0.12 |
0.559 |
0.692 |
68
|
3 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
44
|
888 |
CREBBP |
Q92793
|
CREB binding protein
|
|
1.00 |
0.428 |
0.808 |
40
|
115 |
NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
37
|
14 |
PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
33
|
229 |
C11orf65 |
Q8NCR3
|
chromosome 11 open reading frame 65
|
|
2.0E-14 |
0.670 |
0.462 |
32
|
342 |
FGFR1 |
P11362
|
fibroblast growth factor receptor 1
|
Kinase
|
1.00 |
0.362 |
0.885 |
27
|
63 |
EGFR |
P00533
|
epidermal growth factor receptor
|
Kinase
|
0.37 |
0.295 |
0.885 |
23
|
50 |
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
20
|
682 |
MYCN |
P04198
|
MYCN proto-oncogene, bHLH transcription factor
|
Transcription factor
|
0.89 |
0.454 |
0.808 |
18
|
14 |
FBXW7 |
Q969H0
|
F-box and WD repeat domain containing 7
|
Enzyme modulator
|
1.00 |
0.465 |
0.808 |
18
|
7 |
IDH1 |
O75874
|
isocitrate dehydrogenase (NADP(+)) 1
|
|
2.6E-12 |
0.424 |
0.808 |
18
|
2 |
DNMT3A |
Q9Y6K1
|
DNA methyltransferase 3 alpha
|
|
7.4E-39 |
0.445 |
0.846 |
14
|
22 |
PIK3R1 |
P27986
|
phosphoinositide-3-kinase regulatory subunit 1
|
Kinase
|
1.00 |
0.477 |
0.885 |
10
|
24 |
POLE |
Q07864
|
DNA polymerase epsilon, catalytic subunit
|
|
8.0E-27 |
0.526 |
0.731 |
10
|
9 |
MYCNOS |
P40205
|
MYCN opposite strand
|
|
|
0.700 |
0.462 |
9
|
5 |