Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1899 59
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 995 85
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 706 308
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 556 92
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 551 52
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 536 61
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 532 20
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 470 95
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846 460 15
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 457 17
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 443 160
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846 435 56
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 423 21
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808 422 56
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885 420 68
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846 350 102
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 350 42
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 341 50
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808 340 74
ABCC1 P33527 ATP binding cassette subfamily C member 1 Transporter 1.2E-03 0.445 0.808 333 28
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846 317 75