Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2245 232
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1737 58
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1277 41
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1160 28
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1105 16
ALB P02768 albumin Transporter 0.64 0.317 0.962 1089 13
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 1087 12
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 1077 12
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1029 4
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 957 6
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 757 66
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 748 8
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 665 33
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 652 15
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 593 8
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 576 169
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 546 5
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 520 17
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 517 111
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808 511 0