Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 1394 183
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 687 76
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 447 99
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885 419 44
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 412 38
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 398 8
VCP P55072 valosin containing protein 1.00 0.469 0.923 376 25
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846 369 155
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 334 75
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 321 71
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846 321 5
CXCL1 P09341 C-X-C motif chemokine ligand 1 Signaling 0.12 0.449 0.923 315 3
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769 307 2
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769 289 35
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846 273 47
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808 273 15
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885 260 7
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769 258 16
PAX3 P23760 paired box 3 0.24 0.481 0.769 257 62
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846 254 66
CALM1 P0DP23 P0DP24 P0DP25 calmodulin 1 Calcium-binding protein 0.94 0.472 0.808 253 10
CALM2 P0DP23 P0DP24 P0DP25 calmodulin 2 Calcium-binding protein 0.92 0.472 0.808 252 12
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 249 44
DAPK1 P53355 death associated protein kinase 1 Kinase 1.00 0.472 0.808 249 9