Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 13 34
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692 6 3
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808 5 5
DCLK3 Q9C098 doublecortin like kinase 3 Kinase 0.14 0.647 0.615 5 2
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 5 1
MYO18B Q8IUG5 myosin XVIIIB 1.0E-31 0.628 0.615 4 5
GUCY2F P51841 guanylate cyclase 2F, retinal Kinase 1.1E-13 0.821 0.231 4 2
MAP3K15 Q6ZN16 mitogen-activated protein kinase kinase kinase 15 2.9E-32 0.792 0.231 4 1
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692 4 1
EPHA5 P54756 EPH receptor A5 Kinase 7.3E-05 0.626 0.615 3 2
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846 3 2
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462 3 0
WNK3 Q9BYP7 WNK lysine deficient protein kinase 3 Kinase 1.00 0.751 0.346 3 0
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 2 4
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808 2 1
MYLK4 Q86YV6 myosin light chain kinase family member 4 3.1E-13 0.890 0.154 2 1
FYN P06241 FYN proto-oncogene, Src family tyrosine kinase Kinase 0.99 0.556 0.731 2 0
AURKC Q9UQB9 aurora kinase C Kinase 7.8E-02 0.736 0.308 2 0
TRIM24 O15164 tripartite motif containing 24 1.00 0.581 0.615 2 0
BMP2K Q9NSY1 BMP2 inducible kinase Kinase 0.22 0.792 0.346 1 1
ACVR1C Q8NER5 activin A receptor type 1C Kinase 8.5E-04 0.700 0.423 1 0
MAST4 O15021 microtubule associated serine/threonine kinase family member 4 1.2E-04 0.805 0.346 1 0
PLK1 P53350 polo like kinase 1 Kinase 0.98 0.467 0.808 1 0