Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 280
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 128
ALB P02768 albumin Transporter 0.64 0.317 0.962 122
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 99
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 97
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 97
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 89
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 86
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 66
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 66
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 64
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 59
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885 56
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 53
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 49
TF P02787 transferrin Enzyme 4.1E-08 0.527 0.846 46
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 45
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 45
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 44
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 41
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 38
LMNA P02545 lamin A/C 1.00 0.384 0.885 36
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846 34
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808 31