Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 873 39
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 581 6
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 552 1105
ELN P15502 elastin 2.1E-14 0.415 0.885 545 61
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846 526 2
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808 511 0
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 482 61
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923 467 2
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 454 27
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846 409 88
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 399 8
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 395 31
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769 346 10
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885 341 33
LOX P28300 lysyl oxidase 0.99 0.447 0.846 328 14
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769 327 3
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 321 38
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846 298 32
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769 290 13
CALCR P30988 calcitonin receptor G-protein coupled receptor 3.1E-09 0.464 0.846 282 12
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808 279 72
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731 271 3