Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1511 83
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 1349 384
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1314 146
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 1228 107
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1119 24
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 1101 12
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 1083 13
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 1011 8
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 859 12
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846 702 30
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 671 22
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 603 4
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 594 47
MIR155 microRNA 155 0.384 0.885 584 1
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 565 23