Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 992 56
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 675 21
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 599 6
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 590 59
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 229 9
APLN Q9ULZ1 apelin 0.46 0.497 0.769 226 11
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769 209 39
PAM P19021 peptidylglycine alpha-amidating monooxygenase Enzyme 6.9E-06 0.542 0.692 155 23
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577 126 10
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 103 2
HOMER1 Q86YM7 homer scaffold protein 1 1.00 0.636 0.538 85 3
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423 75 83
C3AR1 Q16581 complement C3a receptor 1 G-protein coupled receptor 3.3E-09 0.601 0.731 73 2
SHCBP1 Q8NEM2 SHC binding and spindle associated 1 9.4E-08 0.606 0.654 72 0
PSD A5PKW4 pleckstrin and Sec7 domain containing 0.90 0.626 0.654 59 8
FLOT1 O75955 flotillin 1 1.0E-08 0.623 0.692 56 4
LRIT1 Q9P2V4 leucine rich repeat, Ig-like and transmembrane domains 1 4.6E-15 0.641 0.615 53 1
GHS Goldenhar syndrome 0.659 0.615 49 0
NAT8L Q8N9F0 N-acetyltransferase 8 like 0.86 0.722 0.346 32 0
USP46 P62068 ubiquitin specific peptidase 46 Enzyme 0.79 0.769 0.192 16 3