Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC39A4 Q6P5W5 solute carrier family 39 member 4 Transporter 3.1E-04 0.628 0.692 49
LPIN2 Q92539 lipin 2 5.0E-05 0.628 0.615 40
ECM1 Q16610 extracellular matrix protein 1 4.7E-14 0.576 0.731 34
IL17RA Q96F46 interleukin 17 receptor A 3.6E-04 0.529 0.808 34
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731 33
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731 32
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846 22
STING1 Q86WV6 stimulator of interferon response cGAMP interactor 1 1.2E-03 0.522 0.769 19
PSTPIP1 O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 2.5E-06 0.650 0.577 17
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 15
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 15
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769 14
TMC6 Q7Z403 transmembrane channel like 6 Ion channel 5.9E-10 0.705 0.308 14
IL7 P13232 interleukin 7 0.93 0.464 0.808 12
TMC8 Q8IU68 transmembrane channel like 8 Ion channel 1.1E-14 0.705 0.231 12
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 11
IL36RN Q9UBH0 interleukin 36 receptor antagonist 3.4E-08 0.638 0.538 6
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 4