Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 423 21
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 400 73
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808 259 19
FZD4 Q9ULV1 frizzled class receptor 4 G-protein coupled receptor 0.97 0.490 0.923 239 28
LRP4 O75096 LDL receptor related protein 4 1.4E-06 0.568 0.692 151 23
SMOC1 Q9H4F8 SPARC related modular calcium binding 1 Calcium-binding protein 9.5E-03 0.565 0.846 135 26
NEDD4L Q96PU5 NEDD4 like E3 ubiquitin protein ligase Enzyme 1.00 0.573 0.731 108 29
WDPCP O95876 WD repeat containing planar cell polarity effector 1.1E-10 0.576 0.769 105 17
JAG2 Q9Y219 jagged canonical Notch ligand 2 1.00 0.576 0.846 81 2
CELSR2 Q9HCU4 cadherin EGF LAG seven-pass G-type receptor 2 G-protein coupled receptor 1.00 0.656 0.577 63 20
ZRS ZPA regulatory sequence 0.722 0.269 21 0
FAM92A A1XBS5 family with sequence similarity 92 member A 5.8E-08 0.729 0.308 17 1