Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 7 45
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731 6 2
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846 5 67
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 5 6
ERN1 O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 0.99 0.513 0.808 5 4
DCLK3 Q9C098 doublecortin like kinase 3 Kinase 0.14 0.647 0.615 5 2
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 4 11
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846 4 8
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 4 2
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731 3 7
CILK1 Q9UPZ9 ciliogenesis associated kinase 1 Kinase 1.3E-05 0.545 0.808 3 4
FLCN Q8NFG4 folliculin 0.79 0.537 0.885 3 3
MERTK Q12866 MER proto-oncogene, tyrosine kinase Kinase 2.7E-11 0.531 0.692 3 2
MYO3A Q8NEV4 myosin IIIA Kinase 1.8E-45 0.780 0.269 3 1
WNK3 Q9BYP7 WNK lysine deficient protein kinase 3 Kinase 1.00 0.751 0.346 3 0
CDK15 Q96Q40 cyclin dependent kinase 15 Kinase 2.2E-17 0.663 0.500 2 1
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885 2 0
BRD3 Q15059 bromodomain containing 3 Epigenetic regulator 0.97 0.700 0.500 2 0
RIOK2 Q9BVS4 RIO kinase 2 Kinase 1.3E-04 0.821 0.154 1 1