| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 | 11 | 17 |
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 | 10 | 32 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 | 8 | 18 |
| EPHA3 | P29320 | EPH receptor A3 | Kinase | 1.2E-05 | 0.497 | 0.692 | 6 | 3 |
| ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 | 4 | 4 |
| NTRK2 | Q16620 | neurotrophic receptor tyrosine kinase 2 | Kinase | 1.00 | 0.479 | 0.808 | 4 | 4 |
| NTRK3 | Q16288 | neurotrophic receptor tyrosine kinase 3 | Kinase | 1.00 | 0.522 | 0.692 | 4 | 2 |
| SLC22A18 | Q96BI1 | solute carrier family 22 member 18 | Transporter | 6.5E-06 | 0.595 | 0.692 | 2 | 1 |
| MXRA5 | Q9NR99 | matrix remodeling associated 5 | 4.3E-02 | 0.839 | 0.192 | 1 | 5 | |
| CSNK2A3 | Q8NEV1 | casein kinase 2 alpha 3 | Kinase | 2.1E-10 | 0.821 | 0.077 | 1 | 1 |