Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 25 99
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 22 20
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 19 64
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 16 16
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 9 22
GLIS3 Q8NEA6 GLIS family zinc finger 3 5.6E-08 0.590 0.654 9 10
SLC30A8 Q8IWU4 solute carrier family 30 member 8 Transporter 7.4E-12 0.623 0.731 9 4
MADD Q8WXG6 MAP kinase activating death domain 1.5E-14 0.644 0.538 7 12
GCK P35557 glucokinase Kinase 0.63 0.523 0.808 7 9
MRPL33 O75394 mitochondrial ribosomal protein L33 0.37 0.792 0.269 7 8
SPC25 Q9HBM1 SPC25 component of NDC80 kinetochore complex 2.6E-02 0.729 0.346 7 4
G6PC2 Q9NQR9 glucose-6-phosphatase catalytic subunit 2 3.0E-16 0.751 0.231 7 2
IGF2BP2 Q9Y6M1 insulin like growth factor 2 mRNA binding protein 2 Enzyme 0.24 0.588 0.615 6 26
ADCY5 O95622 adenylate cyclase 5 1.00 0.617 0.577 6 4
MTNR1B P49286 melatonin receptor 1B G-protein coupled receptor 6.5E-04 0.588 0.731 6 1
GRB10 Q13322 growth factor receptor bound protein 10 Receptor 0.94 0.628 0.615 5 7
ARAP1 Q96P48 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.12 0.769 0.308 5 3
PROX1-AS1 PROX1 antisense RNA 1 0.780 0.231 4 4
SLC2A2 P11168 solute carrier family 2 member 2 Transporter 3.4E-08 0.572 0.692 4 4
PROX1 Q92786 prospero homeobox 1 Transcription factor 1.00 0.565 0.538 4 3
CRY2 Q49AN0 cryptochrome circadian regulator 2 Enzyme 3.2E-04 0.599 0.692 3 3
MIR583HG MIR583 host gene 1.000 3 2
DPYSL5 Q9BPU6 dihydropyrimidinase like 5 Enzyme 1.00 0.644 0.500 3 1