Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 1394 183
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1314 146
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 1228 107
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 877 101
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 873 39
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 859 12
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 686 27
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 647 7
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 590 59
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 536 61
SST P61278 somatostatin Signaling 0.34 0.399 0.885 535 4
CDH1 P12830 cadherin 1 0.15 0.401 0.808 508 187
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769 490 17
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923 455 3
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 454 20
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 440 13
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 437 42
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 423 21
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 402 2
MEN1 O00255 menin 1 1.00 0.444 0.808 364 213