Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 1899 59
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 1394 183
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 995 85
IL2 P60568 interleukin 2 0.48 0.336 0.885 950 5
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 765 43
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 674 3
VIM P08670 vimentin 0.71 0.372 0.846 644 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 635 7
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 626 21
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 623 23
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 616 11
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 587 9
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923 586 34
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 492 30
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885 480 10
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846 456 10
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 439 8