Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 6 19
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846 5 12
ERN1 O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 0.99 0.513 0.808 5 4
GUCY2F P51841 guanylate cyclase 2F, retinal Kinase 1.1E-13 0.821 0.231 4 2
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808 3 4
SIK1 A0A0B4J2F2 P57059 salt inducible kinase 1 Kinase 0.94 0.544 0.731 3 2
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 3 1
TAF1L Q8IZX4 TATA-box binding protein associated factor 1 like Epigenetic regulator 0.96 0.839 0.154 3 0
EPHB6 O15197 EPH receptor B6 Kinase 1.2E-07 0.619 0.538 3 0
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769 2 17
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577 2 2
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 2 2
MAPKAPK3 Q16644 MAPK activated protein kinase 3 Kinase 3.7E-09 0.743 0.308 2 2
INSRR P14616 insulin receptor related receptor Kinase 5.4E-24 0.508 0.808 2 0
IRAK1 P51617 interleukin 1 receptor associated kinase 1 Kinase 0.99 0.506 0.808 2 0
TRIM33 Q9UPN9 tripartite motif containing 33 1.00 0.626 0.577 2 0
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846 2 0
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885 2 0
PTK2 Q05397 protein tyrosine kinase 2 Kinase 1.00 0.497 0.808 2 0
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808 2 0
PDK2 Q15119 pyruvate dehydrogenase kinase 2 Kinase 3.7E-06 0.751 0.269 1 1
CDC42BPG Q6DT37 CDC42 binding protein kinase gamma Kinase 4.6E-26 0.890 0.192 1 1
TRIB3 Q96RU7 tribbles pseudokinase 3 Kinase 1.2E-13 0.573 0.692 1 1
DYRK2 Q92630 dual specificity tyrosine phosphorylation regulated kinase 2 Kinase 1.00 0.670 0.346 1 1