Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 1337 31
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1314 146
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 1193 57
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 633 29
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 599 6
MIR155 microRNA 155 0.384 0.885 584 1
ELN P15502 elastin 2.1E-14 0.415 0.885 545 61
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923 480 9
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 440 33
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846 396 1
MIR221 microRNA 221 0.449 0.846 304 2
MIR29A microRNA 29a 0.459 0.808 278 0
AMH P03971 anti-Mullerian hormone 3.4E-12 0.476 0.846 242 12
THBS2 P35442 thrombospondin 2 0.56 0.526 0.769 149 13
LPAR1 Q92633 lysophosphatidic acid receptor 1 G-protein coupled receptor 0.19 0.534 0.808 145 11
ANGPTL2 Q9UKU9 angiopoietin like 2 Signaling 1.5E-03 0.545 0.731 125 2