| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | 153 | 73 | |
| SOS1 | Q07889 | SOS Ras/Rac guanine nucleotide exchange factor 1 | Enzyme modulator | 1.00 | 0.485 | 0.808 | 62 | 28 |
| ZEB2 | O60315 | zinc finger E-box binding homeobox 2 | Transcription factor | 1.00 | 0.471 | 0.808 | 36 | 96 |
| MEFV | O15553 | MEFV innate immuity regulator, pyrin | 1.0E-14 | 0.440 | 0.885 | 23 | 30 | |
| SZT2 | Q5T011 | SZT2 subunit of KICSTOR complex | 2.3E-14 | 0.670 | 0.423 | 10 | 14 |