Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 69 53
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 52 70
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
THADA Q6YHU6 THADA armadillo repeat containing Receptor 4.6E-41 0.686 0.500 37 33
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
CASC15 cancer susceptibility 15 0.603 0.577 35 41
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 32 19
ZFPM2 Q8WW38 zinc finger protein, FOG family member 2 Transcription factor 1.00 0.565 0.731 30 27
MARK4 Q96L34 microtubule affinity regulating kinase 4 Kinase 1.00 0.641 0.615 28 44
BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor 1.4E-04 0.716 0.538 28 32
CELSR2 Q9HCU4 cadherin EGF LAG seven-pass G-type receptor 2 G-protein coupled receptor 1.00 0.656 0.577 26 8
ARHGAP15 Q53QZ3 Rho GTPase activating protein 15 Enzyme modulator 1.4E-08 0.682 0.462 25 30
SHROOM3 Q8TF72 shroom family member 3 0.32 0.736 0.462 25 29
ATP2B1 P20020 ATPase plasma membrane Ca2+ transporting 1 Transporter 1.00 0.666 0.500 25 19
SOX6 P35712 SRY-box transcription factor 6 1.00 0.578 0.615 24 41
MAD1L1 Q9Y6D9 mitotic arrest deficient 1 like 1 6.8E-16 0.570 0.731 24 38
SMG6 Q86US8 SMG6 nonsense mediated mRNA decay factor 0.98 0.751 0.308 24 36
COL4A2 P08572 collagen type IV alpha 2 chain 3.6E-15 0.563 0.654 23 22
STN1 Q9H668 STN1 subunit of CST complex 2.3E-10 0.604 0.769 23 13