Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 644 54
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 535 65
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 339 239
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846 283 7
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654 270 54
PVT1 Pvt1 oncogene 0.495 0.731 190 38
MIRLET7C microRNA let-7c 0.514 0.808 154 0
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577 129 2
HOXB9 P17482 homeobox B9 0.31 0.572 0.654 83 2
SPI1 P17947 Spi-1 proto-oncogene Transcription factor 0.98 0.631 0.654 58 11
DDX41 Q9UJV9 DEAD-box helicase 41 5.6E-08 0.636 0.538 54 10
VENTX O95231 VENT homeobox Transcription factor 2.7E-05 0.839 0.154 10 0