Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654 7
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 6
DMD P11532 dystrophin 1.00 0.423 0.923 4
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 4
IQSEC2 Q5JU85 IQ motif and Sec7 domain ArfGEF 2 1.00 0.573 0.577 3
ACSL4 O60488 acyl-CoA synthetase long chain family member 4 Enzyme 0.98 0.561 0.769 2
HCFC1 P51610 host cell factor C1 1.00 0.601 0.692 2
RAB39B Q96DA2 RAB39B, member RAS oncogene family 0.83 0.619 0.615 2
UPF3B Q9BZI7 UPF3B regulator of nonsense mediated mRNA decay 0.98 0.619 0.615 2
USP9X Q93008 ubiquitin specific peptidase 9 X-linked 1.00 0.502 0.846 2
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 1
ALG13 Q9NP73 ALG13 UDP-N-acetylglucosaminyltransferase subunit 1.00 0.631 0.577 1
ARHGEF6 Q15052 Rac/Cdc42 guanine nucleotide exchange factor 6 1.00 0.678 0.462 1
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654 1
CNKSR2 Q8WXI2 connector enhancer of kinase suppressor of Ras 2 1.00 0.628 0.538 1
CXorf56 Q9H5V9 chromosome X open reading frame 56 0.95 0.705 0.385 1
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615 1
FRMPD4 Q14CM0 FERM and PDZ domain containing 4 1.00 0.674 0.423 1
FTSJ1 Q9UET6 FtsJ RNA 2'-O-methyltransferase 1 0.99 0.659 0.577 1
GDI1 P31150 GDP dissociation inhibitor 1 Enzyme 0.99 0.572 0.654 1
IL1RAPL1 Q9NZN1 interleukin 1 receptor accessory protein like 1 Receptor 1.00 0.617 0.692 1
MID2 Q9UJV3 midline 2 0.18 0.695 0.500 1
PAK3 O75914 p21 (RAC1) activated kinase 3 Kinase 0.99 0.569 0.731 1
PTCHD1 Q96NR3 patched domain containing 1 Receptor 0.98 0.678 0.385 1