Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 179 27
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 59 11
SST P61278 somatostatin Signaling 0.34 0.399 0.885 56 0
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 53 22
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885 52 33
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 49 320
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 49 1
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 47 2
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 44 22
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846 42 5
RBP4 P02753 retinol binding protein 4 Transporter 0.52 0.493 0.808 36 9
DHFR P00374 dihydrofolate reductase Enzyme 3.4E-02 0.513 0.808 34 3
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885 33 6
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 33 2
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 29 164
IL11 P20809 interleukin 11 3.2E-04 0.481 0.808 29 1
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885 28 32
ITGB4 P16144 integrin subunit beta 4 Receptor 9.5E-19 0.525 0.731 28 25