Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor signaling molecule 0.80 0.263 0.966 343 7
SOD2 P04179 superoxide dismutase 2 oxidoreductase 0.16 0.396 0.897 290 0
IL6 P05231 interleukin 6 0.34 0.287 0.966 271 3
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 1.00 0.338 0.897 243 0
POMC P01189 proopiomelanocortin 9.4E-05 0.382 0.862 238 6
IL1B P01584 interleukin 1 beta 0.13 0.312 0.931 236 1
TP53 P04637 tumor protein p53 transcription factor 0.17 0.251 0.897 217 239
MTHFR P42898 methylenetetrahydrofolate reductase 1.2E-09 0.354 0.828 195 82
NOS2 P35228 nitric oxide synthase 2 1.5E-14 0.385 0.931 178 8
PTEN P60484 phosphatase and tensin homolog hydrolase; phosphatase 0.82 0.334 0.828 177 243
VEGFA P15692 vascular endothelial growth factor A signaling molecule 2.7E-05 0.298 0.897 176 2
IFNA2 P01563 interferon alpha 2 0.459 0.793 172 0
CSF3 P09919 colony stimulating factor 3 0.33 0.421 0.828 169 1
TGFB1 P01137 transforming growth factor beta 1 signaling molecule 0.17 0.336 0.931 168 17
IFNG P01579 interferon gamma 0.47 0.323 0.897 167 0
CAT P04040 catalase oxidoreductase 1.9E-10 0.397 0.828 166 1
KRAS P01116 KRAS proto-oncogene, GTPase enzyme modulator 9.0E-04 0.350 0.724 160 34
SOD1 P00441 superoxide dismutase 1 oxidoreductase 0.13 0.406 0.931 156 35
INS P01308 insulin 0.32 0.458 0.828 150 31
HMOX1 P09601 heme oxygenase 1 oxidoreductase 7.9E-03 0.403 0.862 140 3
AGT P01019 angiotensinogen enzyme modulator 3.9E-08 0.406 0.862 138 12
PLAT P00750 plasminogen activator, tissue type hydrolase; protease 3.5E-05 0.459 0.828 138 0
CCL2 P13500 C-C motif chemokine ligand 2 signaling molecule 0.62 0.353 0.897 138 0
BCL2 P10415 BCL2, apoptosis regulator signaling molecule 0.57 0.312 0.862 137 8