Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 522
Gene Symbol: ATP5PF
ATP5PF 		ATP synthase peripheral stalk subunit F6 0.716 0.538 6.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2016 2016
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB 		platelet derived growth factor subunit B 0.488 0.846 0.77
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 1993 2011
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS 		prostaglandin I2 synthase 0.617 0.654 1.2E-09
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 1999 2004
Entrez Id: 1958
Gene Symbol: EGR1
EGR1 		early growth response 1 0.433 0.923 0.35
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2010 2011
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA 		endothelin receptor type A 0.426 0.885 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2004 2010
Entrez Id: 2697
Gene Symbol: GJA1
GJA1 		gap junction protein alpha 1 0.393 0.885 0.16
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2011 2013
Entrez Id: 284119
Gene Symbol: CAVIN1
CAVIN1 		caveolae associated protein 1 0.559 0.654 5.0E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2012 2013
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		SMAD family member 4 0.401 0.808 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2007 2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2007 2012
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2004 2009
Entrez Id: 387
Gene Symbol: RHOA
RHOA 		ras homolog family member A 0.502 0.808 0.60
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2006 2007
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1 		SMAD family member 1 0.533 0.731 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2007 2008
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		caveolin 1 0.388 0.885 8.3E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 2 0 2004 2013
Entrez Id: 3596
Gene Symbol: IL13
IL13 		interleukin 13 0.386 0.846 1.4E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2009 2009
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A 		phosphodiesterase 3A 0.670 0.577 1.9E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 5154
Gene Symbol: PDGFA
PDGFA 		platelet derived growth factor subunit A 0.533 0.731 0.81
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 1993 1993
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6 		interleukin 6 0.248 0.962 0.32
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2011 2011
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7 		SMAD family member 7 0.470 0.769 0.55
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A 		ATP synthase F1 subunit alpha 0.604 0.731 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2011 2011
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2 		ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 0.529 0.808 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 4878
Gene Symbol: NPPA
NPPA 		natriuretic peptide A 0.505 0.769 5.5E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 1990 1990
Entrez Id: 4609
Gene Symbol: MYC
MYC 		MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 4091
Gene Symbol: SMAD6
SMAD6 		SMAD family member 6 0.579 0.731 3.6E-20
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4312
Gene Symbol: MMP1
MMP1 		matrix metallopeptidase 1 0.385 0.885 7.7E-18
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		phenotype 0.200 None 1.000 1 0 2012 2012