Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
solute carrier family 6 member 4 0.446 0.724 0.26
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 3 0 2001 2009
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.417 0.828 0.46
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 1 0 1995 2011
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.567 0.552 9.1E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 1 0 2005 2011
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.570 0.621 8.2E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.510 1 0 2004 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.401 0.862 8.9E-07
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 3 0 2006 2011
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.482 0.724 1.5E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 2 0 1996 2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.353 0.897 0.62
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 2 0 1998 2008
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
endothelin receptor type B 0.492 0.793 1.2E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 2 0 2004 2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.367 0.793 0.97
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 2 0 2005 2010
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
potassium voltage-gated channel subfamily A member 5 0.648 0.414 1.2E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 1 0 2010 2017
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.447 0.828 0.73
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 1 0 2005 2015
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
nuclear factor of activated T cells 2 0.588 0.517 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 1 0 2007 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.385 0.931 1.5E-14
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.220 1 0 2006 2007
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
angiopoietin 1 0.495 0.690 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 2 0 2004 2008
Entrez Id: 3371
Gene Symbol: TNC
TNC
tenascin C 0.475 0.759 5.6E-07
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 2 0 2005 2009
Entrez Id: 1490
Gene Symbol: CTGF
CTGF
connective tissue growth factor 0.443 0.759 2.8E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 1 0 2005 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 1 0 2002 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.406 0.862 3.9E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 1 0 2004 2011
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
urotensin 2 0.609 0.586 2.9E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 1 0 2004 2005
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
prostaglandin I2 synthase 0.624 0.552 1.4E-09
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 2 0 1999 2004
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
endothelin receptor type A 0.469 0.828 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 2 0 2004 2010
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
early growth response 1 0.459 0.793 0.33
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 2 0 2010 2012
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
SMAD family member 1 0.572 0.552 0.99
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 2 0 2007 2008
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
gap junction protein alpha 1 0.431 0.793 0.14
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 2 0 2011 2013
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
platelet derived growth factor subunit B 0.514 0.690 0.77
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 2 0 1993 2011