Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.300 None 0.917 2 0 1990 2019
Entrez Id: 8435
Gene Symbol: SOAT2
SOAT2
sterol O-acyltransferase 2 0.716 0.308 5.6E-28
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2002 2002
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
phospholipase A2 group VII 0.537 0.769 5.3E-22
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 1996 1996
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
matrix metallopeptidase 1 0.385 0.885 7.7E-18
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 1992 1992
Entrez Id: 8694
Gene Symbol: DGAT1
DGAT1
diacylglycerol O-acyltransferase 1 0.621 0.615 1.4E-17
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2004 2004
Entrez Id: 338
Gene Symbol: APOB
APOB
apolipoprotein B 0.453 0.808 1.9E-16
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.220 None 1.000 1 0 1996 2005
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1
NPHS1 adhesion molecule, nephrin 0.597 0.615 2.5E-14
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.400 None 1.000 1 0 1998 2019
Entrez Id: 50618
Gene Symbol: ITSN2
ITSN2
intersectin 2 0.711 0.423 9.8E-13
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.210 None 1.000 0 0 2018 2018
Entrez Id: 2195
Gene Symbol: FAT1
FAT1
FAT atypical cadherin 1 0.508 0.808 1.2E-12
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.210 None 1.000 0 0 2005 2005
Entrez Id: 6337
Gene Symbol: SCNN1A
SCNN1A
sodium channel epithelial 1 subunit alpha 0.601 0.577 1.1E-11
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2004 2004
Entrez Id: 7436
Gene Symbol: VLDLR
VLDLR
very low density lipoprotein receptor 0.558 0.692 2.0E-11
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 1997 1997
Entrez Id: 2
Gene Symbol: A2M
A2M
alpha-2-macroglobulin 0.529 0.769 4.5E-11
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.510 None 1.000 1 0 1998 2001
Entrez Id: 4358
Gene Symbol: MPV17
MPV17
mitochondrial inner membrane protein MPV17 0.595 0.577 9.7E-11
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.220 None 1.000 0 0 1993 1997
Entrez Id: 57678
Gene Symbol: GPAM
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial 0.792 0.192 1.2E-09
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2008 2008
Entrez Id: 7827
Gene Symbol: NPHS2
NPHS2
NPHS2 stomatin family member, podocin 0.576 0.538 7.2E-09
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.700 None 1.000 1 0 1995 2019
Entrez Id: 1644
Gene Symbol: DDC
DDC
dopa decarboxylase 0.535 0.769 3.8E-08
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2006 2006
Entrez Id: 6338
Gene Symbol: SCNN1B
SCNN1B
sodium channel epithelial 1 subunit beta 0.628 0.577 5.8E-08
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2004 2004
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
acetyl-CoA acetyltransferase 1 0.538 0.692 9.9E-08
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2009 2009
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
lipase C, hepatic type 0.585 0.654 3.3E-07
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 1997 1997
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.210 None 1.000 1 0 1999 2009
Entrez Id: 3758
Gene Symbol: KCNJ1
KCNJ1
potassium inwardly rectifying channel subfamily J member 1 0.619 0.577 4.6E-05
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2011 2011
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.429 0.885 5.5E-04
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.340 None 1.000 1 0 1995 2017
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.200 None 1.000 1 0 2014 2014
Entrez Id: 1514
Gene Symbol: CTSL
CTSL
cathepsin L 0.488 0.846 8.0E-03
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.220 None 1.000 1 0 2004 2018
Entrez Id: 396
Gene Symbol: ARHGDIA
ARHGDIA
Rho GDP dissociation inhibitor alpha 0.663 0.577 3.6E-02
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome
group 0.330 None 1.000 0 0 2013 2015