| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.500 | None | 0.934 | 0 | 0 | 1996 | 2020 | ||||||||
|
WRN RecQ like helicase | 0.524 | 0.808 | 2.6E-34 |
|
disease | 0.180 | None | 1.000 | 0 | 0 | 2006 | 2017 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.955 | 0 | 0 | 1992 | 2020 | ||||||||
|
RAD50 double strand break repair protein | 0.556 | 0.808 | 3.4E-27 |
|
disease | 0.200 | None | 0.824 | 0 | 0 | 2003 | 2018 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2017 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 1994 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | None | 0.952 | 0 | 0 | 2001 | 2019 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 0.500 | None | 0.860 | 0 | 0 | 1996 | 2020 | ||||||||
|
hyaluronan mediated motility receptor | 0.544 | 0.615 | 5.5E-21 |
|
disease | 0.490 | None | 0.889 | 0 | 0 | 2002 | 2019 | ||||||||
|
SEC23 homolog B, COPII coat complex component | 0.579 | 0.692 | 6.1E-20 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.700 | None | 0.961 | 0 | 0 | 2007 | 2020 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 2003 | 2020 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
disease | 0.200 | None | 0.891 | 0 | 0 | 2002 | 2019 | ||||||||
|
RAD54 like | 0.633 | 0.423 | 2.4E-15 |
|
disease | 0.420 | None | 0.500 | 0 | 0 | 2017 | 2017 | ||||||||
|
collagen type XIV alpha 1 chain | 0.674 | 0.615 | 1.4E-14 |
|
disease | 0.100 | None | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.500 | None | 0.969 | 0 | 0 | 2010 | 2019 | ||||||||
|
MRE11 homolog, double strand break repair nuclease | 0.527 | 0.808 | 1.3E-12 |
|
disease | 0.200 | None | 1.000 | 0 | 0 | 2008 | 2019 | ||||||||
|
isocitrate dehydrogenase (NADP(+)) 1 | 0.424 | 0.808 | 2.6E-12 |
|
disease | 0.130 | None | 0.667 | 0 | 0 | 2012 | 2018 | ||||||||
|
protein phosphatase, Mg2+/Mn2+ dependent 1D | 0.513 | 0.808 | 2.2E-11 |
|
disease | 0.500 | None | 0.960 | 0 | 0 | 2002 | 2020 | ||||||||
|
X-ray repair cross complementing 3 | 0.505 | 0.769 | 1.9E-10 |
|
disease | 0.500 | None | 0.915 | 0 | 0 | 2002 | 2019 | ||||||||
|
nth like DNA glycosylase 1 | 0.623 | 0.615 | 5.7E-10 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
RAD51 paralog D | 0.674 | 0.385 | 1.1E-09 |
|
disease | 0.200 | None | 0.923 | 0 | 0 | 2004 | 2019 | ||||||||
|
alpha and gamma adaptin binding protein | 0.695 | 0.538 | 3.9E-07 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.200 | None | 0.944 | 0 | 0 | 2005 | 2019 | ||||||||
|
N-ribosyldihydronicotinamide:quinone reductase 2 | 0.628 | 0.500 | 8.8E-07 |
|
disease | 0.430 | None | 1.000 | 0 | 0 | 2009 | 2011 |