| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.900 | None | 0.971 | 0 | 0 | 1982 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.700 | None | 0.968 | 0 | 0 | 1981 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 1987 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.987 | 0 | 0 | 2001 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.700 | None | 0.966 | 0 | 0 | 1997 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.955 | 0 | 0 | 1992 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 1994 | 2020 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.700 | None | 0.950 | 0 | 0 | 2003 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.700 | None | 0.992 | 0 | 0 | 1999 | 2020 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.700 | None | 0.961 | 0 | 0 | 2007 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.700 | None | 0.952 | 0 | 0 | 2001 | 2019 | ||||||||
|
caspase 8 | 0.404 | 0.923 | 3.7E-06 |
|
disease | 0.700 | None | 0.980 | 0 | 0 | 2004 | 2019 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.500 | None | 0.934 | 0 | 0 | 1996 | 2020 | ||||||||
|
prohibitin | 0.511 | 0.846 | 0.76 |
|
disease | 0.500 | None | 0.944 | 0 | 0 | 1993 | 2018 | ||||||||
|
protein phosphatase, Mg2+/Mn2+ dependent 1D | 0.513 | 0.808 | 2.2E-11 |
|
disease | 0.500 | None | 0.960 | 0 | 0 | 2002 | 2020 | ||||||||
|
X-ray repair cross complementing 3 | 0.505 | 0.769 | 1.9E-10 |
|
disease | 0.500 | None | 0.915 | 0 | 0 | 2002 | 2019 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 0.500 | None | 0.860 | 0 | 0 | 1996 | 2020 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.500 | None | 0.969 | 0 | 0 | 2010 | 2019 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.500 | None | 0.944 | 0 | 0 | 1997 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.500 | None | 0.899 | 0 | 0 | 1994 | 2020 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
disease | 0.500 | None | 0.943 | 0 | 0 | 1996 | 2020 | ||||||||
|
MDM2 proto-oncogene | 0.362 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.922 | 0 | 0 | 1993 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.500 | None | 0.964 | 0 | 0 | 1995 | 2020 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.500 | None | 1.000 | 0 | 0 | 1991 | 2019 | ||||||||
|
hyaluronan mediated motility receptor | 0.544 | 0.615 | 5.5E-21 |
|
disease | 0.490 | None | 0.889 | 0 | 0 | 2002 | 2019 |