| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
transglutaminase 2 | 0.445 | 0.808 | 6.8E-18 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 1997 | 2019 | ||||||||
|
matrix metallopeptidase 1 | 0.385 | 0.885 | 7.7E-18 |
|
phenotype | 0.400 | None | 0.989 | 3 | 0 | 1993 | 2020 | ||||||||
|
matrix metallopeptidase 13 | 0.452 | 0.923 | 7.9E-18 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 1999 | 2019 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
phenotype | 0.600 | None | 0.991 | 18 | 0 | 1996 | 2020 | ||||||||
|
serpin family B member 4 | 0.623 | 0.423 | 8.8E-17 |
|
phenotype | 0.020 | None | 1.000 | 1 | 0 | 2006 | 2008 | ||||||||
|
integrin subunit alpha 1 | 0.644 | 0.654 | 2.6E-16 |
|
phenotype | 0.030 | None | 1.000 | 1 | 0 | 2004 | 2018 | ||||||||
|
advanced glycosylation end-product specific receptor | 0.420 | 0.885 | 6.4E-16 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 2002 | 2019 | ||||||||
|
gap junction protein beta 2 | 0.441 | 0.846 | 6.6E-16 |
|
phenotype | 0.070 | None | 1.000 | 2 | 0 | 2004 | 2013 | ||||||||
|
protein phosphatase 1 regulatory subunit 3A | 0.711 | 0.577 | 9.3E-16 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
cytochrome P450 family 2 subfamily J member 2 | 0.628 | 0.615 | 1.6E-15 |
|
phenotype | 0.020 | None | 1.000 | 1 | 0 | 2007 | 2016 | ||||||||
|
erb-b2 receptor tyrosine kinase 3 | 0.448 | 0.808 | 1.7E-15 |
|
phenotype | 0.400 | None | 0.969 | 3 | 0 | 1998 | 2019 | ||||||||
|
TNF receptor superfamily member 10a | 0.521 | 0.731 | 5.1E-15 |
|
phenotype | 0.040 | None | 1.000 | 1 | 0 | 2001 | 2018 | ||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 13 | 0.496 | 0.769 | 5.1E-15 |
|
phenotype | 0.040 | None | 1.000 | 1 | 0 | 2002 | 2018 | ||||||||
|
matrix metallopeptidase 3 | 0.408 | 0.885 | 5.7E-15 |
|
phenotype | 0.300 | None | 1.000 | 1 | 0 | 2002 | 2020 | ||||||||
|
heparanase | 0.425 | 0.808 | 2.3E-14 |
|
phenotype | 0.400 | None | 0.972 | 15 | 0 | 1999 | 2020 | ||||||||
|
cadherin 17 | 0.636 | 0.615 | 3.4E-14 |
|
phenotype | 0.100 | None | 0.833 | 2 | 0 | 2004 | 2018 | ||||||||
|
GLI family zinc finger 1 | 0.431 | 0.846 | 7.7E-14 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 2006 | 2019 | ||||||||
|
UDP glucuronosyltransferase family 1 member A7 | 0.550 | 0.692 | 8.7E-14 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
serpin family A member 3 | 0.486 | 0.846 | 8.8E-14 |
|
phenotype | 0.030 | None | 1.000 | 1 | 0 | 2004 | 2018 | ||||||||
|
inter-alpha-trypsin inhibitor heavy chain 3 | 0.769 | 0.231 | 1.5E-13 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
alpha-1-microglobulin/bikunin precursor | 0.537 | 0.731 | 2.8E-13 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 2000 | 2012 | ||||||||
|
HIV-1 Tat interactive protein 2 | 0.608 | 0.577 | 5.4E-13 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 2000 | 2019 | ||||||||
|
laminin subunit gamma 2 | 0.389 | 0.923 | 2.9E-12 |
|
phenotype | 0.100 | None | 1.000 | 1 | 0 | 1996 | 2019 | ||||||||
|
keratin 7 | 0.463 | 0.808 | 3.1E-12 |
|
phenotype | 0.060 | None | 1.000 | 1 | 0 | 2008 | 2019 | ||||||||
|
caspase 10 | 0.528 | 0.692 | 4.6E-12 |
|
phenotype | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 |