Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.700 None 0.947 3 0 1991 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.500 None 1.000 2 0 1999 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.500 None 0.981 1 0 1988 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.400 None 0.931 2 0 1994 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.400 None 1.000 1 0 1992 2020
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.330 None 1.000 1 0 2001 2017
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.310 None 1.000 1 0 2008 2011
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.160 None 1.000 1 0 1994 2007
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
prominin 1 0.410 0.846 1.9E-22
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.100 None 0.955 2 0 2004 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.090 None 1.000 1 0 1998 2018
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.374 0.846 0.99
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.080 None 0.875 2 0 2001 2015
Entrez Id: 1755
Gene Symbol: DMBT1
DMBT1
deleted in malignant brain tumors 1 0.533 0.654 4.5E-63
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.080 None 1.000 2 0 1997 2013
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.080 None 1.000 1 0 2000 2016
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.070 None 1.000 1 0 2004 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.070 None 1.000 1 0 2008 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.060 None 1.000 1 0 2004 2017
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
glutathione S-transferase theta 1 0.393 0.923 1.5E-04
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.060 None 0.667 1 0 1997 2016
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
MYCN proto-oncogene, bHLH transcription factor 0.454 0.808 0.89
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.050 None 1.000 1 0 2008 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.050 None 0.800 1 0 1997 2013
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
solute carrier family 2 member 1 0.388 0.808 0.99
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.050 None 1.000 1 0 1994 2004
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
glutathione S-transferase pi 1 0.383 0.923 1.4E-02
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.050 None 0.800 1 0 2002 2016
Entrez Id: 3791
Gene Symbol: KDR
KDR
kinase insert domain receptor 0.378 0.885 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.040 None 1.000 1 0 2002 2010
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.406 0.808 0.90
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.040 None 1.000 1 0 2002 2015
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
matrix metallopeptidase 14 0.447 0.769 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.040 None 1.000 1 0 2008 2016
Entrez Id: 3485
Gene Symbol: IGFBP2
IGFBP2
insulin like growth factor binding protein 2 0.478 0.769 0.12
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.030 None 1.000 1 0 2001 2010