Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
nucleotide binding oligomerization domain containing 2 0.458 0.862 1.6E-30
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.900 0.909 60 0 1998 2018
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
interleukin 23 receptor 0.505 0.724 7.0E-04
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.500 0.923 11 0 2006 2017
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
autophagy related 16 like 1 0.586 0.586 0.94
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.500 0.927 9 0 2001 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.359 0.931 5.6E-09
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.500 0.833 3 0 2004 2018
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
immunity related GTPase M 0.648 0.345
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.500 0.913 3 0 2007 2018
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.320 0.931 6.5E-03
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.500 0.945 2 0 1996 2018
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
neutrophil cytosolic factor 4 0.690 0.345 8.6E-08
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.450 0.600 1 0 2008 2017
Entrez Id: 219771
Gene Symbol: CCNY
CCNY
cyclin Y 0.720 0.207 0.83
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.420 1.000 1 0 2008 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.944 8 0 1996 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.897 2 0 1992 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.323 0.897 0.47
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.885 2 0 1993 2016
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.399 0.862 3.7E-03
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.929 2 0 2001 2015
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
NLR family pyrin domain containing 3 0.435 0.862 7.0E-04
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.857 2 0 2004 2015
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
solute carrier family 11 member 1 0.537 0.793 3.5E-19
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.700 2 0 1997 2016
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
NK2 homeobox 3 0.762 0.069 0.94
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.929 1 0 2007 2015
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.347 0.897 1.0E-03
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.400 0.870 1 0 1995 2015
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.399 0.828 1.2E-03
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.330 1.000 1 0 2007 2010
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
solute carrier family 22 member 4 0.676 0.483 1.3E-08
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.200 0.879 5 0 2004 2012
Entrez Id: 9966
Gene Symbol: TNFSF15
TNFSF15
TNF superfamily member 15 0.584 0.621 3.0E-03
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.200 1.000 2 0 2004 2017
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
TNF receptor superfamily member 1A 0.443 0.862 1.00
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.170 1.000 1 0 2002 2017
Entrez Id: 55600
Gene Symbol: ITLN1
ITLN1
intelectin 1 0.743 0.310 3.1E-06
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.120 1.000 1 0 2005 2013
Entrez Id: 3683
Gene Symbol: ITGAL
ITGAL
integrin subunit alpha L 0.547 0.793 5.0E-03
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.110 1 0 2002 2017
Entrez Id: 56244
Gene Symbol: BTNL2
BTNL2
butyrophilin like 2 0.619 0.621 9.2E-11
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.110 1 0 2007 2014
Entrez Id: 6584
Gene Symbol: SLC22A5
SLC22A5
solute carrier family 22 member 5 0.663 0.552 1.5E-15
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.100 0.913 6 0 2004 2011
Entrez Id: 9231
Gene Symbol: DLG5
DLG5
discs large MAGUK scaffold protein 5 0.713 0.276 1.00
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 0.100 0.762 6 0 2004 2014