Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
tachykinin precursor 1 0.424 0.923 0.75
CUI: C0030193
Disease: Pain
Pain
phenotype 0.600 None 0.960 1 0 1993 2020
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
cannabinoid receptor 1 0.446 0.808 0.51
CUI: C0030193
Disease: Pain
Pain
phenotype 0.600 None 1.000 1 0 2009 2020
Entrez Id: 1312
Gene Symbol: COMT
COMT
catechol-O-methyltransferase 0.400 0.923 1.1E-06
CUI: C0030193
Disease: Pain
Pain
phenotype 0.600 None 0.958 1 0 2003 2020
Entrez Id: 5020
Gene Symbol: OXT
OXT
oxytocin/neurophysin I prepropeptide 0.615 0.423 0.71
CUI: C0030193
Disease: Pain
Pain
phenotype 0.500 None 1.000 1 0 1984 2007
Entrez Id: 623
Gene Symbol: BDKRB1
BDKRB1
bradykinin receptor B1 0.619 0.731 4.7E-03
CUI: C0030193
Disease: Pain
Pain
phenotype 0.500 None 1.000 1 0 2007 2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 1.000 2 0 2002 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 0.981 1 0 2004 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 1.000 1 0 2008 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 0.952 1 0 2008 2020
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 1.000 1 0 2001 2019
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
opioid receptor mu 1 0.457 0.808 7.9E-11
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 0.965 1 0 1999 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 0.973 1 0 1998 2020
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
cannabinoid receptor 2 0.509 0.846 6.5E-06
CUI: C0030193
Disease: Pain
Pain
phenotype 0.300 None 1.000 1 0 2007 2019
Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1
opioid receptor delta 1 0.604 0.731 3.3E-03
CUI: C0030193
Disease: Pain
Pain
phenotype 0.290 None 1.000 1 0 2003 2020
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
tachykinin receptor 1 0.502 0.885 3.8E-04
CUI: C0030193
Disease: Pain
Pain
phenotype 0.280 None 1.000 1 0 2001 2019
Entrez Id: 729230
Gene Symbol: CCR2
CCR2
C-C motif chemokine receptor 2 0.418 0.846 2.3E-02
CUI: C0030193
Disease: Pain
Pain
phenotype 0.270 None 1.000 1 0 2008 2018
Entrez Id: 885
Gene Symbol: CCK
CCK
cholecystokinin 0.453 0.846 3.3E-05
CUI: C0030193
Disease: Pain
Pain
phenotype 0.260 None 1.000 1 0 2007 2019
Entrez Id: 3606
Gene Symbol: IL18
IL18
interleukin 18 0.365 0.923 3.1E-02
CUI: C0030193
Disease: Pain
Pain
phenotype 0.260 None 1.000 1 0 2009 2019
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
prostaglandin-endoperoxide synthase 1 0.460 0.885 6.2E-07
CUI: C0030193
Disease: Pain
Pain
phenotype 0.250 None 1.000 2 0 2004 2017
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
C-X3-C motif chemokine receptor 1 0.457 0.885 6.1E-02
CUI: C0030193
Disease: Pain
Pain
phenotype 0.250 None 1.000 1 0 2009 2019
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
nerve growth factor receptor 0.477 0.846 9.8E-02
CUI: C0030193
Disease: Pain
Pain
phenotype 0.230 None 1.000 1 0 2010 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0030193
Disease: Pain
Pain
phenotype 0.230 None 1.000 1 0 2008 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0030193
Disease: Pain
Pain
phenotype 0.230 None 1.000 1 0 2010 2018
Entrez Id: 834
Gene Symbol: CASP1
CASP1
caspase 1 0.413 0.885 3.5E-05
CUI: C0030193
Disease: Pain
Pain
phenotype 0.230 None 1.000 1 0 2009 2019
Entrez Id: 199
Gene Symbol: AIF1
AIF1
allograft inflammatory factor 1 0.521 0.808 1.9E-06
CUI: C0030193
Disease: Pain
Pain
phenotype 0.220 None 1.000 1 0 2008 2019