| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
phenotype | 0.500 | None | 1.000 | 0 | 0 | 2002 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
phenotype | 0.500 | None | 0.966 | 0 | 0 | 2002 | 2020 | ||||||||
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
phenotype | 0.500 | None | 0.994 | 0 | 0 | 1993 | 2020 | ||||||||
|
FMRP translational regulator 1 | 0.473 | 0.769 | 0.65 |
|
phenotype | 0.160 | None | 1.000 | 0 | 0 | 2010 | 2017 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
phenotype | 0.140 | None | 1.000 | 0 | 0 | 2017 | 2020 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
phenotype | 0.140 | None | 1.000 | 0 | 0 | 2015 | 2019 | ||||||||
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
phenotype | 0.140 | None | 1.000 | 0 | 0 | 2007 | 2017 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
phenotype | 0.130 | None | 1.000 | 0 | 0 | 2017 | 2019 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
phenotype | 0.130 | None | 1.000 | 0 | 0 | 2015 | 2019 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
phenotype | 0.130 | None | 1.000 | 0 | 0 | 2018 | 2018 | |||||||||
|
C9orf72-SMCR8 complex subunit | 0.496 | 0.769 | 1.1E-06 |
|
phenotype | 0.130 | None | 1.000 | 0 | 0 | 2013 | 2017 | ||||||||
|
ceruloplasmin | 0.466 | 0.846 | 4.2E-10 |
|
phenotype | 0.120 | None | 1.000 | 0 | 0 | 2018 | 2018 | ||||||||
|
ATP binding cassette subfamily A member 7 | 0.644 | 0.577 | 2.1E-55 |
|
phenotype | 0.120 | None | 1.000 | 0 | 0 | 2016 | 2019 | ||||||||
|
Fas cell surface death receptor | 0.372 | 0.923 | 0.81 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
sodium voltage-gated channel alpha subunit 2 | 0.518 | 0.731 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2018 | 2018 | ||||||||
|
atrophin 1 | 0.409 | 0.885 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2012 | 2012 | ||||||||
|
xenotropic and polytropic retrovirus receptor 1 | 0.488 | 0.731 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2010 | 2010 | ||||||||
|
MYD88 innate immune signal transduction adaptor | 0.414 | 0.923 | 0.12 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
eukaryotic translation initiation factor 2B subunit delta | 0.659 | 0.538 | 0.96 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
eukaryotic translation initiation factor 2B subunit beta | 0.647 | 0.538 | 2.1E-10 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
colony stimulating factor 1 receptor | 0.448 | 0.808 | 0.13 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2018 | 2018 | ||||||||
|
proline rich transmembrane protein 2 | 0.448 | 0.808 | 0.58 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2018 | 2018 | ||||||||
|
DNA methyltransferase 1 | 0.406 | 0.885 | 1.00 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
eukaryotic translation initiation factor 2B subunit alpha | 0.663 | 0.538 | 7.6E-05 |
|
phenotype | 0.110 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
twinkle mtDNA helicase | 0.516 | 0.692 | 3.2E-03 |
|
phenotype | 0.100 | None | 0 | 0 |